Air versus oxygen in myocardial infarction (AVOID) trial sub-study: time-dependent effect of oxygen administration on myocardial injury
نویسندگان
چکیده
منابع مشابه
A randomized controlled trial of oxygen therapy in acute myocardial infarction Air Verses Oxygen In myocarDial infarction study (AVOID Study).
BACKGROUND The role of routine supplemental oxygen for patients with uncomplicated acute myocardial infarction (AMI) has recently been questioned. There is conflicting data on the possible effects of hyperoxia on ischemic myocardium. The few clinical trials examining the role of oxygen in AMI were performed prior to the modern approach of emergent reperfusion and advanced medical management. ...
متن کاملOxygen therapy in myocardial infarction.
HIGH concentration oxygen therapy is often required after acute myocardial infarction, as hypoxia is common and may be resistant to oxygen therapy (MacKenzie et al., 1964; McNicol et al., 1965). While 100% oxygen is probably the treatment of choice, the apparatus for its administration, a tight-fitting face mask with valve box and reservoir or demand valve, is poorly tolerated and requires cons...
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The circulatory responses to high equinalgesic doses of morphine are compared with those of pethidin. The decrease in mean arterial blood pressure in case of morphine was 28p.c., with a paralleled and identical decrease in total peripheral resistance and no negative inotropic effects. Pethidine decreased blood pressure 54p.c., as a result of peripheral vasodilation of 46p.c. and a sharp drop...
متن کاملControlled trial of oxygen in uncomplicated myocardial infarction.
Two-hundred consecutive patients thought to have suffered a myocardial infarction were admitted to a randomised, double-blind controlled trial of oxygen or air administered by MC mask throughout the first 24 hours in hospital. Forty-three patients in whom myocardial infarction was not subsequently confirmed were excluded from the analysis. The remaining air and oxygen groups were comparable exc...
متن کاملLetter by Bulluck and Hausenloy Regarding Article, "Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction".
BACKGROUND Oxygen is commonly administered to patients with ST-elevation-myocardial infarction despite previous studies suggesting a possible increase in myocardial injury as a result of coronary vasoconstriction and heightened oxidative stress. METHODS AND RESULTS We conducted a multicenter, prospective, randomized, controlled trial comparing oxygen (8 L/min) with no supplemental oxygen in p...
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ژورنال
عنوان ژورنال: Heart, Lung and Circulation
سال: 2015
ISSN: 1443-9506
DOI: 10.1016/j.hlc.2015.06.609